发明申请
- 专利标题： Antisense modulation of stearoyl-CoA desaturase expression
- 专利标题（中）： 硬脂酰-CoA去饱和酶表达的反义调制
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申请号： US11613144申请日： 2006-12-19
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公开(公告)号： US20080153766A1公开(公告)日： 2008-06-26
- 发明人: Sanjay Bhanot , Kenneth W. Dobie , John G. Geisler , Mark J. Graham
- 申请人： Sanjay Bhanot , Kenneth W. Dobie , John G. Geisler , Mark J. Graham
- 主分类号： A61K31/7088
- IPC分类号： A61K31/7088 ; C07H21/04 ; A61P43/00 ; A61P3/10
摘要：
Antisense compounds, compositions and methods are provided for modulating the expression of stearoyl-CoA desaturase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding stearoyl-CoA desaturase. Methods of using these compounds for modulation of stearoyl-CoA desaturase expression and for treatment of diseases associated with expression of stearoyl-CoA desaturase are provided.
公开/授权文献
- US07960358B2 Antisense modulation of stearoyl-CoA desaturase expression 公开/授权日：2011-06-14
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