发明申请
- 专利标题： Serine hydrolase inhibitors
- 专利标题（中）： 丝氨酸水解酶抑制剂
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申请号： US11903483申请日： 2007-09-20
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公开(公告)号： US20080161290A1公开(公告)日： 2008-07-03
- 发明人: Kevin Shreder , Yi Hu , Allister Fraser , Yasushi Kohno , Akihiko Kojima , Junichi Ishiyama
- 申请人： Kevin Shreder , Yi Hu , Allister Fraser , Yasushi Kohno , Akihiko Kojima , Junichi Ishiyama
- 主分类号： A61K31/551
- IPC分类号： A61K31/551 ; C07D265/12 ; A61K31/536 ; C07D295/00 ; A61P19/02 ; A61P11/00 ; A61K31/541 ; C07D243/08
摘要：
Provided herein are benzoxazinone compounds of formula I and compositions containing the compounds. The compounds and compositions are useful in the methods of inhibiting the action of serine hydrolase, including neutrophil elastase. In certain embodiments, the compounds and compositions are useful in the prevention, amelioration or treatment of serine hydrolase-mediated diseases.
公开/授权文献
- US07879846B2 Serine hydrolase inhibitors 公开/授权日：2011-02-01
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