发明申请
US20080161363A1 2-Aminopyridine Compounds Useful as Beta-Secretase Inhibitors For the Treatment of Alzheimer's Disease
有权
用作治疗阿尔茨海默病的β-分泌酶抑制剂的2-氨基吡啶化合物
- 专利标题: 2-Aminopyridine Compounds Useful as Beta-Secretase Inhibitors For the Treatment of Alzheimer's Disease
- 专利标题(中): 用作治疗阿尔茨海默病的β-分泌酶抑制剂的2-氨基吡啶化合物
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申请号: US11666942申请日: 2005-10-25
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公开(公告)号: US20080161363A1公开(公告)日: 2008-07-03
- 发明人: Craig A. Coburn , M. Katharine Holloway , Shawn J. Stachel
- 申请人: Craig A. Coburn , M. Katharine Holloway , Shawn J. Stachel
- 国际申请: PCT/US05/39932 WO 20051025
- 主分类号: A61K31/4965
- IPC分类号: A61K31/4965 ; A61K31/501
摘要:
The present invention is directed to 2-aminopyridine compounds which are inhibitors of the beta-secretase enzyme and that are useful in the treatment of diseases in which the beta-secretase enzyme is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the treatment of such diseases in which the beta-secretase enzyme is involved.
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