发明申请
US20080166299A1 Acetylene Derivatives And Their Use For Binding And Imaging Amyloid Plaques
失效
乙炔衍生物及其用于结合和成像淀粉样斑块的用途
- 专利标题: Acetylene Derivatives And Their Use For Binding And Imaging Amyloid Plaques
- 专利标题(中): 乙炔衍生物及其用于结合和成像淀粉样斑块的用途
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申请号: US11951612申请日: 2007-12-06
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公开(公告)号: US20080166299A1公开(公告)日: 2008-07-10
- 发明人: Hank F. Kung , Mei Ping Kung
- 申请人: Hank F. Kung , Mei Ping Kung
- 申请人地址: US PA Philadelphia
- 专利权人: Trustees of The University of Pennsylvania
- 当前专利权人: Trustees of The University of Pennsylvania
- 当前专利权人地址: US PA Philadelphia
- 主分类号: A61K51/04
- IPC分类号: A61K51/04 ; C07C211/43 ; A61K31/135 ; C07C43/205 ; A61P25/28 ; A61K31/085 ; C07D213/02 ; A61K31/44
摘要:
The invention relates to radiolabeled compounds and their use in methods of imaging amyloid deposits, as well as to methods of their manufacture. The invention also relates to compounds for inhibiting the aggregation of amyloid proteins that form amyloid deposits, methods for delivering therapeutic agents to amyloid deposits, as well as methods of making compounds that inhibit the aggregation of amyloid proteins.
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