发明申请
- 专利标题: Modulation of pathogenicity
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申请号: US12005763申请日: 2007-12-28
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公开(公告)号: US20080188536A1公开(公告)日: 2008-08-07
- 发明人: Aldo Ammendola , Katharina Aulinger-Fuchs , Astrid Gotschlich , Bernd Kramer , Martin Lang , Wael Saeb , Udo Sinks , Andreas Wuzik
- 申请人: Aldo Ammendola , Katharina Aulinger-Fuchs , Astrid Gotschlich , Bernd Kramer , Martin Lang , Wael Saeb , Udo Sinks , Andreas Wuzik
- 主分类号: A61K31/415
- IPC分类号: A61K31/415 ; C07D231/40 ; A01N43/56 ; A61P31/04 ; A01P1/00
摘要:
The present invention relates to the use of compounds of the general Formula (I): wherein in Formula (I), R is H, alkyl, cycloalkyl, aryl or heteroaryl; R1 is H, alkyl, cycloalkyl, aryl or heteroaryl; R2 is H, alkyl, cycloalkyl, aryl or heteroaryl; A1 and A2 each independently represent an optionally substituted C1-C20-alkyl group which may contain one or more group(s) Z, or a monocyclic or polycyclic optionally substituted aromatic or non-aromatic ring system which may contain one or more group(s) X, and in case of a polycyclic ring system, said system contains at least one aromatic ring; Z is selected from the group consisting of S, O, N, NR4, CO, CO2, CS, SO or SO2 X is selected from the group consisting of S, O, N, NR4, SO or SO2;
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