发明申请
US20080194573A1 3-(Heteroaryl-Oxy)-2-Alkyl-1-Aza-Bicycloalkyl Derivatives As Alpha. 7-Nachrligands For TheTreatment Of Cns Diseases
审中-公开
3-(杂芳基 - 氧基)-2-烷基-1-氮杂 - 双环烷基衍生物。 用于治疗CNS疾病的7名患者
- 专利标题: 3-(Heteroaryl-Oxy)-2-Alkyl-1-Aza-Bicycloalkyl Derivatives As Alpha. 7-Nachrligands For TheTreatment Of Cns Diseases
- 专利标题(中): 3-(杂芳基 - 氧基)-2-烷基-1-氮杂 - 双环烷基衍生物。 用于治疗CNS疾病的7名患者
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申请号: US11571536申请日: 2005-07-13
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公开(公告)号: US20080194573A1公开(公告)日: 2008-08-14
- 发明人: Dominik Feuerbach , Mathias Frederiksen , Konstanze Hurth , Bernard Lucien Roy
- 申请人: Dominik Feuerbach , Mathias Frederiksen , Konstanze Hurth , Bernard Lucien Roy
- 申请人地址: CH Basel
- 专利权人: NOVARTIS AG
- 当前专利权人: NOVARTIS AG
- 当前专利权人地址: CH Basel
- 优先权: GB0415746.7 20040714
- 国际申请: PCT/EP05/07630 WO 20050713
- 主分类号: A61K31/501
- IPC分类号: A61K31/501 ; C07D471/08 ; A61K31/439 ; A61K31/506 ; A61P25/18
摘要:
The present invention relates to 1-aza-bicycloalkyl derivatives of formula (I) wherein the substituents are as defined in the specification, to processes for their production, their use as pharmaceuticals in the prevention and treatment of psychotic and neurodegenerative disorders. The claimed compounds act as nicotinic acelylcholine receptors (NACHR) ligands.
公开/授权文献
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