发明申请
US20080194574A1 Pyrazine Derivatives As Effective Compounds Against Infectious Diseases
审中-公开
吡嗪衍生物作为有效的化合物对抗传染病
- 专利标题： Pyrazine Derivatives As Effective Compounds Against Infectious Diseases
- 专利标题（中）： 吡嗪衍生物作为有效的化合物对抗传染病
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申请号： US10596508申请日： 2004-12-16
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公开(公告)号： US20080194574A1公开(公告)日： 2008-08-14
- 发明人: Jan Eike Eikhoff , Mark Richard Ashton , Stephen Martin Courtney , Christopher John Yarnold , Maurizio Varrone , Pui Leng Loke , Thomas Herget , Wilfried Schwab , Doris Hafenbradl
- 申请人： Jan Eike Eikhoff , Mark Richard Ashton , Stephen Martin Courtney , Christopher John Yarnold , Maurizio Varrone , Pui Leng Loke , Thomas Herget , Wilfried Schwab , Doris Hafenbradl
- 申请人地址： DE Munich
- 专利权人： AXXIMA PHARMACEUTICALS AG
- 当前专利权人： AXXIMA PHARMACEUTICALS AG
- 当前专利权人地址： DE Munich
- 优先权： EP03029038.1 20031216
- 国际申请： PCT/EP2004/014371 WO 20041216
- 主分类号： A61K31/4985
- IPC分类号： A61K31/4985 ; C07D487/04 ; C07D241/10 ; A61K31/4965 ; A61P31/00 ; A61P37/00 ; A61P25/16 ; A61P25/28
摘要：
The present invention relates to pyrazine derivatives according to the general formula (I) and pharmaceutically acceptable salts thereof and their use as pharmaceutical compounds as well as the use of these compounds for the preparation of a pharmaceutical composition for the prophylaxis and/or treatment of infectious diseases, including opportunistic diseases, prion diseases, immunological diseases, autoimmune diseases, bipolar and clinical disorders, cardiovascular diseases, cell proliferative diseases, diabetes, inflammation, transplant rejections, erectile dysfunction, neurodegenerative diseases, stroke and especially for the treatment of herpesviral induced infections, including opportunistic infections as well as infections and diseases caused by human cytomegalovirus (HCMV).