发明申请
US20080194616A1 PYRIDOPYRIMIDINONE COMPOUNDS USEFUL IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS
审中-公开
吡咯并吡啶酮化合物可用于治疗钠通道介导的疾病或病症
- 专利标题： PYRIDOPYRIMIDINONE COMPOUNDS USEFUL IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS
- 专利标题（中）： 吡咯并吡啶酮化合物可用于治疗钠通道介导的疾病或病症
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申请号： US12026435申请日： 2008-02-05
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公开(公告)号： US20080194616A1公开(公告)日： 2008-08-14
- 发明人: Shifeng Liu , Jianmin Fu , Rajender Kamboj , Sultan Chowdhury , Qi Jia , Mark Wood , Jianyu Sun
- 申请人： Shifeng Liu , Jianmin Fu , Rajender Kamboj , Sultan Chowdhury , Qi Jia , Mark Wood , Jianyu Sun
- 申请人地址： CA Burnaby
- 专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人： Xenon Pharmaceuticals Inc.
- 当前专利权人地址： CA Burnaby
- 主分类号： A61K31/444
- IPC分类号： A61K31/444 ; C07D471/02 ; A61P29/00
摘要：
This invention is directed to pyridopyrimidinone compounds of formula (I): wherein n, R1, R2 and R3 are as defined herein, as a stereoisomer, enantiomer, tautomer thereof or mixtures thereof; or a pharmaceutically acceptable salt, solvate or prodrug thereof, useful for the treatment and/or prevention of sodium channel-mediated diseases or conditions, such as pain.
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