发明申请
- 专利标题: Process For Production of Optically Active Ppar-Activating Compound and Intermediate of the Same
- 专利标题(中): 光活性活性化合物及其中间体的制备方法
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申请号: US11816472申请日: 2006-02-23
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公开(公告)号: US20080194833A1公开(公告)日: 2008-08-14
- 发明人: Yukiyoshi Yamazaki , Takaaki Araki , Minoru Koura , Kimiyuki Shibuya
- 申请人: Yukiyoshi Yamazaki , Takaaki Araki , Minoru Koura , Kimiyuki Shibuya
- 申请人地址: JP Nagoya-shi
- 专利权人: Kowa Co., Ltd.
- 当前专利权人: Kowa Co., Ltd.
- 当前专利权人地址: JP Nagoya-shi
- 优先权: JP2005-047476 20050223
- 国际申请: PCT/JP2006/303245 WO 20060223
- 主分类号: C07D263/58
- IPC分类号: C07D263/58
摘要:
A process for obtaining a compound (1) and an intermediate thereof in high yield and high optical yield is provided.A process for producing a compound (4), the process including reacting a compound (2) with a compound (3) in the presence of a base; and a process for producing a compound (1), the process including reacting a compound (2) with a compound (3) in the presence of a base to yield a compound (4) and then deesterifying the compound (4). wherein R represents an alkyl group having 1 to 6 carbon atoms or an aralkyl group having 7 to 8 carbon atoms.
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