发明申请
US20080194877A1 Benzamidine Derivatives for Treatment and Prevention of Cancer Therapy Induced Mucositis
审中-公开
用于治疗和预防癌症治疗诱导粘膜炎的苄脒衍生物
- 专利标题: Benzamidine Derivatives for Treatment and Prevention of Cancer Therapy Induced Mucositis
- 专利标题(中): 用于治疗和预防癌症治疗诱导粘膜炎的苄脒衍生物
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申请号: US11909287申请日: 2006-03-16
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公开(公告)号: US20080194877A1公开(公告)日: 2008-08-14
- 发明人: Ornella Letari , Massimo Maria D'Amato , Simona Zanzola , Roberto Artusi , Lucio Claudio Rovati , Gianfranco Caselli , Antonio Giordani
- 申请人: Ornella Letari , Massimo Maria D'Amato , Simona Zanzola , Roberto Artusi , Lucio Claudio Rovati , Gianfranco Caselli , Antonio Giordani
- 申请人地址: IT Milano
- 专利权人: ROTTAPHARM S.p.A.
- 当前专利权人: ROTTAPHARM S.p.A.
- 当前专利权人地址: IT Milano
- 优先权: EP05102423.0 20050324
- 国际申请: PCT/EP06/60789 WO 20060316
- 主分类号: C07C251/06
- IPC分类号: C07C251/06
摘要:
Mucositis is the result of a complex process of interactive biologic phenomena that take place in both the epitelium and the submucosa, often leading to severe pain and increased risk of dangerous syste f48 mic infections. Mucositis is often a side effect during chemotherapy and radiation therapy. The benzamidine derivatives herein described are particularly effective for treating and preventing mucositis since they are acting simultaneously at the several phases that characterize this disease. Data supplied from the esp@cenet database
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