发明申请
- 专利标题: HETEROMONOCYCLIC COMPOUND AND USE THEREOF
- 专利标题(中): 异环化合物及其用途
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申请号: US11943910申请日: 2007-11-21
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公开(公告)号: US20080207654A1公开(公告)日: 2008-08-28
- 发明人: Takanobu Kuroita , Hiroki Sakamoto , Hideyuki Igawa , Minoru Sasaki , Kouhei Asano , Tsuyoshi Maekawa
- 申请人: Takanobu Kuroita , Hiroki Sakamoto , Hideyuki Igawa , Minoru Sasaki , Kouhei Asano , Tsuyoshi Maekawa
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 优先权: JP317839/2006 20061124; JP232106/2007 20070906
- 主分类号: A61K31/506
- IPC分类号: A61K31/506 ; C07D239/22 ; A61P3/10 ; A61P3/04
摘要:
A compound represented by the formula (I): wherein R1 is an oxo group, ═N—R or the like; a group represented by the formula: is a group represented by the formula: R2 is a group represented by the formula: R3 and R4 are each H, or C1-C6 alkyl, C3-C6 cycloalkyl, C1-C6 alkoxy, C1-C6 alkylamino, di(C1-C6)alkylamino or C1-C6 alkylthio, each of which is optionally substituted; and R5 is H, or C1-C6 alkyl, C2-C6 alkenyl, cyclic group, each of which is optionally substituted, —CO—R8 or —O—R8′, or a salt thereof. The compound of the present invention is useful as a drug for the prophylaxis or treatment of circulatory diseases, metabolic diseases and/or central nervous system diseases.
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