A cargo handling system and method employing a plurality of slide units and tracks. The tracks are mounted in or on a floor of a cargo area of a mobile platform, and also on a ramp of the mobile platform. The slide units slide within the tracks and enable container roll in, roll out platforms (CROPs) and 1077 flatracks to be slidably moved into and out from the cargo area. The slide units are arranged at the four corners of each CROP or 1077 flatrack and can be positively locked to a CROP or 1077 flatrack by a standard ISO twist lock assembly. The slide units eliminate the need for a K-loader and a crane to be present at the site where loading or unloading is to occur. Instead, suitable vehicles such a Heavy Expanded Mobility Tactical Trucks (HEMTTs), which are more readily transported to remote cites, can be used to assist in slidably loading and offloading CROPs and 1077 flatracks.