发明申请
US20080221080A1 Method of Treating Mixed Lineage Leukemia Gene-Rearranged Acute Lymphoblastic Leukemias
审中-公开
治疗混合谱系白血病基因重排的急性淋巴细胞性白血病的方法
- 专利标题： Method of Treating Mixed Lineage Leukemia Gene-Rearranged Acute Lymphoblastic Leukemias
- 专利标题（中）： 治疗混合谱系白血病基因重排的急性淋巴细胞性白血病的方法
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申请号： US10569708申请日： 2003-08-25
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公开(公告)号： US20080221080A1公开(公告)日： 2008-09-11
- 发明人: James Douglas Griffin , Doriano Fabbro
- 申请人： James Douglas Griffin , Doriano Fabbro
- 国际申请： PCT/US2003/026629 WO 20030825
- 主分类号： A61K31/553
- IPC分类号： A61K31/553 ; A61P35/02
摘要：
The present invention relates to a method of treating a warm-blooded animal, especially a human, having Mixed Lineage Leukemia (MLL rearranged ALL) comprising administering to said animal a therapeutically effective amount of a staurosporine derivative, especially PKC412 or a pharmaceutically acceptable salt thereof, alone or in combination with further therapeutic measures, for example, those defined herein; to the use of a staurosporine derivative for the preparation of a medicament for the treatment of MLL rearranged ALL; and to a commercial package comprising a staurosporine derivative together with instructions for its use in the treatment of MLL rearranged ALL.
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