A portable cooler assembly comprises a base and a collapsible container defining a cooler. The collapsible container includes collapsible walls. The base defines a container receiving recess within which a bottom portion of the collapsible container is received, whereby the collapsible container is removably coupled to the base. When the portable cooler assembly is in a first configuration, the collapsible walls extend outwardly from the container receiving space. When the portable cooler assembly is in a second configuration, the collapsible walls are completely received within the container receiving space in a collapsed condition.