发明申请
US20080226652A1 Binding molecules capable of neutralizing rabies virus and uses thereof
有权
能够中和狂犬病病毒的结合分子及其用途
- 专利标题: Binding molecules capable of neutralizing rabies virus and uses thereof
- 专利标题(中): 能够中和狂犬病病毒的结合分子及其用途
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申请号: US11978742申请日: 2007-10-29
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公开(公告)号: US20080226652A1公开(公告)日: 2008-09-18
- 发明人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
- 申请人: Alexander Berthold Hendrik Bakker , Willem Egbert Marissen , Robert Arjen Kramer , Cornelis Adriaan De Kruif
- 专利权人: Crucell Holland B.V.
- 当前专利权人: Crucell Holland B.V.
- 优先权: EPPCT/EP2004/050943 20040527; EPPCT/EP2004/051661 20040729; EPPCT/EP2004/052286 20040923; EPPCT/EP2004/052772 20041103; EPPCT/EP2005/050310 20050125; EPPCT/EP2005/050953 20050303
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61P43/00
摘要:
Provided are binding molecules that specifically bind to rabies virus and are capable of neutralizing the virus. Further provided are nucleic acid molecules encoding the binding molecules, compositions comprising the binding molecules and methods of identifying or producing the binding molecules. The binding molecules can be used in the diagnosis, prophylaxis and/or treatment of a condition resulting from rabies virus. In certain embodiments, they can be used in the post-exposure prophylaxis of rabies.
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