发明申请
- 专利标题： Dimeric Azacyclic Compounds and Their Use
- 专利标题（中）： 二甲基偶氮化合物及其用途
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申请号： US10586838申请日： 2005-02-01
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公开(公告)号： US20080242668A1公开(公告)日： 2008-10-02
- 发明人: Dan Peters , Gunnar M. Olsen , Elsebet Ostergaard Nielsen , Tino Dyhring Jorgensen , Daniel B. Timmermann
- 申请人： Dan Peters , Gunnar M. Olsen , Elsebet Ostergaard Nielsen , Tino Dyhring Jorgensen , Daniel B. Timmermann
- 优先权： DKPA200400470 20040204
- 国际申请： PCT/EP2005/050403 WO 20050201
- 主分类号： A61K31/498
- IPC分类号： A61K31/498 ; C07D221/02 ; A61K31/4375 ; A61P9/00 ; A61P29/00 ; A61P25/00 ; C07D403/02
摘要：
This invention relates to azacyclic derivatives according of formula (I) and their use as pharmaceuticals. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or. disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the′ termination of abuse of chemical substances. Formula (I) Aza-X′-A′-Y′-L-Y-A″-X″-Aza Aza:Azabicyclic group A′,A″:Aromatic monocyclic and/or polycyclic, carbocyclic and/or heterocyclic group Y′,Y″: Linker or absent (covalent bond) L: Monocyclic or polycyclic, carbocyclic or heterocyclic group or is absent X′,X″: Linker or absent (covalent bond)
公开/授权文献
- US07674899B2 Dimeric azacyclic compounds and their use 公开/授权日：2010-03-09
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