Invention Application
- Patent Title: Oxymethyl Boron Compounds
- Patent Title (中): 氧甲基硼化合物
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Application No.: US11886340Application Date: 2006-03-13
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Publication No.: US20080242859A1Publication Date: 2008-10-02
- Inventor: Keigo Tanaka , Satoshi Inoue , Daisuke Ito , Norio Murai , Yosuke Kaburagi , Shuji Shirotori , Shuichi Suzuki , Yoshiaki Ohashi
- Applicant: Keigo Tanaka , Satoshi Inoue , Daisuke Ito , Norio Murai , Yosuke Kaburagi , Shuji Shirotori , Shuichi Suzuki , Yoshiaki Ohashi
- Applicant Address: JP Toyko
- Assignee: Eisai R&D Management Co., Ltd
- Current Assignee: Eisai R&D Management Co., Ltd
- Current Assignee Address: JP Toyko
- Priority: JP2005-070607 20050314; JP2005-294589 20051007
- International Application: PCT/JP2006/304894 WO 20060313
- Main IPC: C07F5/02
- IPC: C07F5/02

Abstract:
The present invention provides compounds which are useful as safe substitutes for the organotin reagent used in coupling reaction for the oxymethylation of aromatic rings, such as alkoxymethylation or hydroxymethylation, with a palladium catalyst and which can dispense with chromatographic purification with silica gel in the production and are suitable for mass production; and compounds applicable even to the oxymethylation of aromatic ring substrates which do not permit coupling reaction by conventional technique or have low reactivity.
Public/Granted literature
- US07696347B2 Oxymethyl boron compounds Public/Granted day:2010-04-13
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