An active power conditioner includes a first power electronic switch set, a second power electronic switch set, a third power electronic switch set, an input filter and an output filter. The active power conditioner can supply a stable AC voltage to a load when a voltage variation is occurred at an AC power source by controlling either the second power electronic switch set or the third power electronic switch set via high-frequency switching, and the other power electronic switch sets that are not switched in high frequency are controlled to switch in low-frequency switching.