发明申请
- 专利标题： Method and Nucleic Acids for the Improved Treatment of Breast Cell Proliferative Disorders
- 专利标题（中）： 改善乳腺增生性疾病治疗的方法和核酸
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申请号： US10582705申请日： 2004-12-13
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公开(公告)号： US20080254447A1公开(公告)日： 2008-10-16
- 发明人: John Foekens , Nadia Harbeck , Thomas Koenig , Sabine Maier , John Martens , Fabian Model , Inko Nimmrich , Manfred Schmitt , Ralf Lesche , Dimo Dietrich , Volkmar Mueller , Antje Kluth , Ina Schwope , Oliver Hartmann , Peter Adorjan , Almuth Marx , Heinz Hoefler
- 申请人： John Foekens , Nadia Harbeck , Thomas Koenig , Sabine Maier , John Martens , Fabian Model , Inko Nimmrich , Manfred Schmitt , Ralf Lesche , Dimo Dietrich , Volkmar Mueller , Antje Kluth , Ina Schwope , Oliver Hartmann , Peter Adorjan , Almuth Marx , Heinz Hoefler
- 申请人地址： DE Berlin
- 专利权人： Epigenomics AG
- 当前专利权人： Epigenomics AG
- 当前专利权人地址： DE Berlin
- 优先权： EP03090432.0 20031211; EP04090041.7 20040210; EP04090127.4 20040401; EP04013328.2 20040605; EP04090380.9 20040930; EP04027213.0 20041116
- 国际申请： PCT/EP2004/014170 WO 20041213
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; C07H21/04
摘要：
The present invention relates to modified and genomic sequences, to oligonucleotides and/or PNA-oligomers for detecting the cytosine methylation state of genomic DNA, as well as to a method for predicting the disease free survival and/or response of a subject with a cell proliferative disorder of the breast tissues, to endocrine treatment.
公开/授权文献
- US09017944B2 Methods for the prognosis of breast cancer 公开/授权日：2015-04-28
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