发明申请
- 专利标题： PHARMACEUTICALLY ACTIVE BENZSULFONAMIDE DERIVATIVES AS INHIBITORS OF PROTEIN JUNKINASES
- 专利标题（中）： 作为蛋白酶的抑制剂的药物活性苯甲酰胺衍生物
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申请号： US12142296申请日： 2008-06-19
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公开(公告)号： US20080255222A1公开(公告)日： 2008-10-16
- 发明人: Serge HALAZY , Dennis Church , Stephen J. Arkinstall , Marco Biamonte , Montserrat Camps , Jean-Pierre Gotteland , Thomas Rueckle
- 申请人： Serge HALAZY , Dennis Church , Stephen J. Arkinstall , Marco Biamonte , Montserrat Camps , Jean-Pierre Gotteland , Thomas Rueckle
- 申请人地址： NL Curacao
- 专利权人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
- 当前专利权人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
- 当前专利权人地址： NL Curacao
- 优先权： EP00810888.8 20000927
- 主分类号： A61K31/395
- IPC分类号： A61K31/395 ; C07D295/26 ; A61P25/28 ; A61P35/00 ; A61P9/10
摘要：
The present invention relates to benzsulfonamide derivatives of formula I and methods of use thereof. The benzsulfonamide derivatives of the present invention are efficient modulators of the JNK pathway. In particular the benzsulfonamide derivatives of the present invention are selective inhibitors of JNK 2 and 3.