发明申请
- 专利标题: Peptide Inhibitors for Mediating Stress Responses
- 专利标题(中): 用于中介应激反应的肽抑制剂
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申请号: US11573707申请日: 2005-08-23
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公开(公告)号: US20080267983A1公开(公告)日: 2008-10-30
- 发明人: Johannes Herkel , Irun R. Cohen , Varda Rotter , Ansgar W. Lohse , Neta Erez , Avishai Mimran , Na'aman Kam
- 申请人: Johannes Herkel , Irun R. Cohen , Varda Rotter , Ansgar W. Lohse , Neta Erez , Avishai Mimran , Na'aman Kam
- 申请人地址: IL Rehovot
- 专利权人: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
- 当前专利权人: YEDA RESEARCH AND DEVELOPMENT CO. LTD.
- 当前专利权人地址: IL Rehovot
- 国际申请: PCT/IL2005/000908 WO 20050823
- 主分类号: A61K39/00
- IPC分类号: A61K39/00 ; C07K2/00 ; C07K7/06 ; A61P25/00 ; A61P29/00 ; C07K7/08 ; C07K14/00
摘要:
The present invention relates to peptides capable of inhibiting cellular and immune stress responses in a eukaryotic cell. The invention provides compositions and methods for the treatment of human degenerative diseases and inflammation, utilizing peptides recognized by monoclonal anti-DNA antibodies, the peptides having anti-apoptotic and anti-inflammatory activity. The invention further provides antibody molecules and uses thereof for the isolation of such peptides.
公开/授权文献
- US08067008B2 Peptide inhibitors for mediating stress responses 公开/授权日:2011-11-29
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