发明申请
US20080269280A1 OXO-IMIDAZOLIDINES AS MODULATORS OF CHEMOKINE RECEPTORS
有权
OXO-IMIDAZOLIDINES作为化合物受体的调节剂
- 专利标题： OXO-IMIDAZOLIDINES AS MODULATORS OF CHEMOKINE RECEPTORS
- 专利标题（中）： OXO-IMIDAZOLIDINES作为化合物受体的调节剂
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申请号： US12048814申请日： 2008-03-14
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公开(公告)号： US20080269280A1公开(公告)日： 2008-10-30
- 发明人: Penglie Zhang , Andrew M.K. Pennell , Lianfa Li , Edward J. Sullivan
- 申请人： Penglie Zhang , Andrew M.K. Pennell , Lianfa Li , Edward J. Sullivan
- 申请人地址： US CA Mountain View
- 专利权人： ChemoCentryx, Inc.
- 当前专利权人： ChemoCentryx, Inc.
- 当前专利权人地址： US CA Mountain View
- 主分类号： A61K31/437
- IPC分类号： A61K31/437 ; C07D233/02 ; C07D261/06 ; C07D401/04 ; A61K31/4166 ; A61K31/422 ; A61P37/02
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally monocyclic and bicyclic compounds and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.
公开/授权文献
- US07786157B2 OXO-imidazolidines as modulators of chemokine receptors 公开/授权日：2010-08-31
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