发明申请
- 专利标题： Formulation of Albumin-Free Erythropoietin
- 专利标题（中）： 无白蛋白红细胞生成素的配方
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申请号： US10567475申请日： 2004-07-27
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公开(公告)号： US20080274949A1公开(公告)日： 2008-11-06
- 发明人: Cheong Weon Cho , Soon Kwan Chung , Jeong Ku , Jun Hee Cheon , Tae Kun An , Eun Kyung Jeon , Jae Kyoung Ko , Tae Hyoung Kim , Yeong Ok Beak , Hea Ran Suh
- 申请人： Cheong Weon Cho , Soon Kwan Chung , Jeong Ku , Jun Hee Cheon , Tae Kun An , Eun Kyung Jeon , Jae Kyoung Ko , Tae Hyoung Kim , Yeong Ok Beak , Hea Ran Suh
- 专利权人： CJ CHEILJEDANG CORPORATION
- 当前专利权人： CJ CHEILJEDANG CORPORATION
- 优先权： KR10-2003-0054260 20030806
- 国际申请： PCT/KR2004/001891 WO 20040727
- 主分类号： A61K38/22
- IPC分类号： A61K38/22
摘要：
Disclosed is a stable pharmaceutical solution preparation of erythropoietin (EPO), which includes a stabilizing agent not containing a blood-derived protein, thereby maintaining EPO activity for a prolonged period of time without the risk of viral contamination. The stable solution preparation further includes a non-ionic surfactant and a tonicity agent, thereby preventing EPO loss during storage and facilitating administration to the body.