发明申请
- 专利标题： Antibody-Drug Conjugates and Methods of Use
- 专利标题（中）： 抗体药物偶联物及其使用方法
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申请号： US12088066申请日： 2006-09-26
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公开(公告)号： US20080279868A1公开(公告)日： 2008-11-13
- 发明人: Sharon Elaine Boyd , Liang Chen , Sanjeev Gangwar , Vincent Guerlavais , Kilian Horgan , Bilal Sufi , Haichun Huang , David John King , Chin Pan , Josephine M. Cardarelli
- 申请人： Sharon Elaine Boyd , Liang Chen , Sanjeev Gangwar , Vincent Guerlavais , Kilian Horgan , Bilal Sufi , Haichun Huang , David John King , Chin Pan , Josephine M. Cardarelli
- 申请人地址： US NJ Princeton
- 专利权人： Medarex, Inc.
- 当前专利权人： Medarex, Inc.
- 当前专利权人地址： US NJ Princeton
- 国际申请： PCT/US06/37793 WO 20060926
- 主分类号： A61K39/39
- IPC分类号： A61K39/39 ; A61K39/44 ; A61P35/00
摘要：
The present disclosure provides antibody-drug conjugates that are potent cytotoxins, wherein the drug is linked to the antibody through a linker. The disclosure is also directed to compositions containing the antibody-drug conjugates, and to methods of treatment using them.
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