发明申请
- 专利标题： Antibody glycosylation variants having increased antibody-dependent cellular cytotoxicity
- 专利标题（中）： 抗体糖基化变体具有增加的抗体依赖性细胞毒性
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申请号： US11199232申请日： 2005-08-09
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公开(公告)号： US20080280322A9公开(公告)日： 2008-11-13
- 发明人: Pablo Umana , Joel Jean-Mairet , James Bailey
- 申请人： Pablo Umana , Joel Jean-Mairet , James Bailey
- 申请人地址： CH Zurich
- 专利权人： GlycArt Biotechnology AG
- 当前专利权人： GlycArt Biotechnology AG
- 当前专利权人地址： CH Zurich
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C07H21/04 ; C12P21/06 ; C12N5/06
摘要：
The present invention relates to the field of glycosylation engineering of proteins. More particularly, the present invention relates to glycosylation engineering to generate proteins with improved therapeutic properties, including antibodies with increased antibody-dependent cellular cytotoxicity.