发明申请
US20080286810A1 Use of Inhibtors of Glutaminyl Cyclases for Treatment and Prevention of Disease
有权
谷氨酰胺酰化酶抑制剂用于治疗和预防疾病的应用
- 专利标题： Use of Inhibtors of Glutaminyl Cyclases for Treatment and Prevention of Disease
- 专利标题（中）： 谷氨酰胺酰化酶抑制剂用于治疗和预防疾病的应用
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申请号： US12101497申请日： 2008-04-11
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公开(公告)号： US20080286810A1公开(公告)日： 2008-11-20
- 发明人: Hans-Ulrich Demuth , Torsten Hoffmann , Andre Johannes Niestroj , Stephan Schilling , Ulrich Heiser
- 申请人： Hans-Ulrich Demuth , Torsten Hoffmann , Andre Johannes Niestroj , Stephan Schilling , Ulrich Heiser
- 申请人地址： DE Halle (Saale)
- 专利权人： PROBIODRUG AG
- 当前专利权人： PROBIODRUG AG
- 当前专利权人地址： DE Halle (Saale)
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C12Q1/00
摘要：
Novel physiological substrates of mammalian glutaminyl cyclase (QC, EC 2.3.2.5), new effectors of QC, methods for screening for such effectors, and the use of such effectors and pharmaceutical compositions comprising such effectors for the treatment of conditions that can be treated by modulation of QC-activity. Preferred compositions additionally comprise inhibitors of DP IV or DP IV-like enzymes for the treatment or alleviation of conditions that can be treated by modulation of QC- and DP IV-activity.
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