Method of generating a number of steps constituting an adaptable clinical workflow based on a recursive approach in which for each step of the workflow the following steps are executed: Selecting a number of knowledge bases to be included in a reasoning step on the basis of (a) goal(s), generating (a) query(ies) taking into account the goal(s), applying the selected knowledge bases and the generated queries to a reasoning engine so as to generate a solution, interpreting this solution by translating the solution given in a formal representation into (an) executable action(s) for the current step in the clinical workflow.