发明申请
US20080293709A1 Novel 2-Amino-Heterocycles Useful in the Treatment of Abeta-Related Pathologies
审中-公开
新型2-氨基杂环可用于治疗与Abeta相关的病理学
- 专利标题: Novel 2-Amino-Heterocycles Useful in the Treatment of Abeta-Related Pathologies
- 专利标题(中): 新型2-氨基杂环可用于治疗与Abeta相关的病理学
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申请号: US12093631申请日: 2006-11-13
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公开(公告)号: US20080293709A1公开(公告)日: 2008-11-27
- 发明人: Jeffrey Albert , Gianni Chessari , Miles Stuart Congreve , Phil Edwards , Christopher Murray , Sahil Patel , Mark Sylvester
- 申请人: Jeffrey Albert , Gianni Chessari , Miles Stuart Congreve , Phil Edwards , Christopher Murray , Sahil Patel , Mark Sylvester
- 申请人地址: SE Sodertalje
- 专利权人: AstraZeneca AB
- 当前专利权人: AstraZeneca AB
- 当前专利权人地址: SE Sodertalje
- 国际申请: PCT/SE06/01283 WO 20061113
- 主分类号: A61K31/472
- IPC分类号: A61K31/472 ; A61P25/00 ; C07D217/22 ; C07D401/02 ; A61K31/517 ; C07D495/04 ; A61K31/536 ; A61K31/4725 ; C07D239/72 ; C07D265/14
摘要:
This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salts, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.
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