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发明申请
US20080299041A1 HETEROCYCLIC INDENE DERIVATIVES AND THEIR RADIOISOTOPE LABELED COMPOUNDS FOR IMAGING BETA-AMYLOID DEPOSITION 审中-公开
杂环衍生物及其用于成像淀粉样沉积物的放射性标记化合物

HETEROCYCLIC INDENE DERIVATIVES AND THEIR RADIOISOTOPE LABELED COMPOUNDS FOR IMAGING BETA-AMYLOID DEPOSITION
摘要：
The invention is directed to heterocyclic indene derivatives useful for β-amyloid plaque imaging, their radiolabeled compounds and their preparation methods. The compounds of the invention are easily labeled with radioisotopes and have high affinities to β-amyloid depositions, thus they facilitate diagnosis of Alzheimer's disease by imaging the distribution of β-amyloid depositions.
摘要（中）：

本发明涉及可用于β-淀粉样蛋白斑块成像的杂环茚衍生物，其放射性标记的化合物及其制备方法。 本发明的化合物容易用放射性同位素标记，并且对β-淀粉样蛋白沉积具有高亲和力，因此它们通过成像β-淀粉样蛋白沉积的分布来促进阿尔茨海默病的诊断。

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