发明申请
- 专利标题: NOVEL BIOMATERIALS, THEIR PREPARATION AND USE
- 专利标题(中): 新生物材料,其制备和使用
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申请号: US12178934申请日: 2008-07-24
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公开(公告)号: US20080299166A1公开(公告)日: 2008-12-04
- 发明人: Lajos Szente , Jozsef Szejtli , Gyorgy L. Kis , Christian Schoch
- 申请人: Lajos Szente , Jozsef Szejtli , Gyorgy L. Kis , Christian Schoch
- 优先权: EP02008809.2 20020419
- 主分类号: A61K47/30
- IPC分类号: A61K47/30 ; A61K47/40 ; A61F2/00 ; A61K38/02 ; A61P17/02 ; A61K31/56 ; A61K38/43
摘要:
The present invention relates to novel materials, particularly biomaterials, in form of a precipitate, comprising at least an anionic polymeric component which is as such soluble in water and an amphiphilic ammonium-type component, which precipitate is obtainable by a process including the following steps: 1. contacting the anionic polymeric component and an cyclodextrin component in an aqueous medium, and 2. adding to the mixture obtained in step 1 said amphiphilic ammonium-type component, wherein said components are present in amounts effective to form said precipitate, and preferably to corresponding precipitates additionally comprising said cyclodextrin component. Both types of precipitates may optionally comprise one or more further components. The precipitates are particularly useful as controlled-release depot formulations suitable for long-lasting delivery of said further components. The further components incorporated into the precipitates can be pharmaceutical compounds, pesticides, agrochemicals, colorants, diagnostics, enzymes, foodstuffs etc.