发明申请
![3-(IMIDAZOLYL)-PYRAZOLO[3,4-b]PYRIDINES](/docs/US/2008-12-04/US20080300257A1/abs.jpg.600x600.jpg)
- 专利标题： 3-(IMIDAZOLYL)-PYRAZOLO[3,4-b]PYRIDINES
- 专利标题（中）： 3-（咪唑烷基） - 吡唑并[3,4-b]吡啶
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申请号： US12124894申请日： 2008-05-21
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公开(公告)号： US20080300257A1公开(公告)日： 2008-12-04
- 发明人: Lianfa Li , Andrew M.K. Pennell , Penglie Zhang
- 申请人： Lianfa Li , Andrew M.K. Pennell , Penglie Zhang
- 申请人地址： US CA Mountain View
- 专利权人： ChemoCentryx, Inc.
- 当前专利权人： ChemoCentryx, Inc.
- 当前专利权人地址： US CA Mountain View
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; C07D471/04 ; A61P37/02 ; A61P29/00 ; A61P25/28 ; A61P25/16
![3-(IMIDAZOLYL)-PYRAZOLO[3,4-b]PYRIDINES](/abs-image/US/2008/12/04/US20080300257A1/abs.jpg.150x150.jpg)
摘要：
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are 3-imidazoyl-pyrazolo[3,4-b]pyridine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.
公开/授权文献
- US07629344B2 3-(imidazolyl)-pyrazolo[3,4-b]pyridines 公开/授权日：2009-12-08
信息查询
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