Invention Application
US20080300408A1 Process for Preparing a Pure Polymorphic Form of 3-Pyridyl-1-Hydroxyethylidine-1, 1-Bisphosphonic Acid Sodium Salt
审中-公开
制备3-吡啶基-1-羟基乙基-1,1-二膦酸钠盐的纯多形态的方法
- Patent Title: Process for Preparing a Pure Polymorphic Form of 3-Pyridyl-1-Hydroxyethylidine-1, 1-Bisphosphonic Acid Sodium Salt
- Patent Title (中): 制备3-吡啶基-1-羟基乙基-1,1-二膦酸钠盐的纯多形态的方法
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Application No.: US11718857Application Date: 2006-08-21
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Publication No.: US20080300408A1Publication Date: 2008-12-04
- Inventor: Satish Chandra Pandey , Khushi Ram , Manoj Kumar Singh , Rajesh Kumar Thaper , Sushil Kumar Dubey
- Applicant: Satish Chandra Pandey , Khushi Ram , Manoj Kumar Singh , Rajesh Kumar Thaper , Sushil Kumar Dubey
- Applicant Address: IN Noida, Uttar Pradesh
- Assignee: JUBILANT ORGANOSYS LIMITED
- Current Assignee: JUBILANT ORGANOSYS LIMITED
- Current Assignee Address: IN Noida, Uttar Pradesh
- International Application: PCT/IN04/00345 WO 20060821
- Main IPC: C07F9/58
- IPC: C07F9/58

Abstract:
This process in general relates to the novel process for preparing polymorphic forms of 3-pyridyl-1-hydroxyethylidine-1,1-bisphosphonic acid sodium salt (Risedronate Sodium) in particular risedronate Form A and B employing a solvent system in an appropriate ratio. An improved process for preparation of risedronic acid is also disclosed in the present invention.
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