Methods for detecting a salient object in an input image are described. For this, the salient object in an image may be defined using a set of local, regional, and global features including multi-scale contrast, center-surround histogram, and color spatial distribution. These features are optimally combined through conditional random field learning. The learned conditional random field is then used to locate the salient object in the image. The methods can also use image segmentation, where the salient object is separated from the image background.