发明申请
- 专利标题: Aminodiazepines as Toll-Like Receptor Modulators
- 专利标题(中): 氨基二氮卓作为Toll样受体调节剂
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申请号: US12064196申请日: 2006-08-17
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公开(公告)号: US20080306050A1公开(公告)日: 2008-12-11
- 发明人: George A. Doherty , Zachary Jones
- 申请人: George A. Doherty , Zachary Jones
- 申请人地址: CO Boulder
- 专利权人: ARRAY BIOPHARMA INC.
- 当前专利权人: ARRAY BIOPHARMA INC.
- 当前专利权人地址: CO Boulder
- 国际申请: PCT/US2006/032099 WO 20060817
- 主分类号: A61K31/5513
- IPC分类号: A61K31/5513 ; C07D243/14 ; A61P37/02
摘要:
Provided are compositions and methods useful for modulation signaling through the Toll-like receptor TLR8. The compositions and methods have use in the treatment of autoimmunity, inflammation allergy, asthma, graft rejection, graft versus host disease, infection, sepsis, cancer and immunodeficiency.
公开/授权文献
- US08163738B2 Aminodiazepines as toll-like receptor modulators 公开/授权日:2012-04-24
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