File protocols for transaction based communication are described. In one embodiment, a method to provide a file transfer protocol includes receiving packets containing headers, the packets being received at a first network stack software through an interface, and extracting data from he packets and reconstructing a file from data in the packets. The extracting may be performed by a first network stack software, and the interface is not designed to use Internet Protocol (IP) addresses, and the headers contain data for flow control and sequencing and are associated with a port for a file transfer application, and the headers allow multiple applications to maintain multiple concurrent sessions through the interface, which may be a USB compliant or BLUETOOTH compliant interface. Systems, computer readable media, software architectures and other methods are also described.