发明申请
US20080312253A1 Pharmaceutical compositions containing pyrazole derivatives for treating as serotonin antagonist
审中-公开
含有用作5-羟色胺拮抗剂治疗的吡唑衍生物的药物组合物
- 专利标题： Pharmaceutical compositions containing pyrazole derivatives for treating as serotonin antagonist
- 专利标题（中）： 含有用作5-羟色胺拮抗剂治疗的吡唑衍生物的药物组合物
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申请号： US12213067申请日： 2008-06-13
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公开(公告)号： US20080312253A1公开(公告)日： 2008-12-18
- 发明人: Ghil Soo Nam , Hye Whon Rhim , Ae Nim Pae , Kyung II Choi , Hyun Ah Choo , Seung Yeol Nah
- 申请人： Ghil Soo Nam , Hye Whon Rhim , Ae Nim Pae , Kyung II Choi , Hyun Ah Choo , Seung Yeol Nah
- 申请人地址： KR Seoul
- 专利权人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- 当前专利权人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- 当前专利权人地址： KR Seoul
- 优先权： KR10-2007-0058542 20070614
- 主分类号： A61K31/496
- IPC分类号： A61K31/496 ; A61P25/16 ; A61P25/28 ; A61P25/18
摘要：
The present invention relates to a pharmaceutical composition containing a pyrazole derivative as an active ingredient, which has antagonistic activity against serotonin 5-HT3A and is effective for the prevention and treatment of central nervous system (CNS) diseases, including emesis, nausea, alcoholism, drug abuse, depression, compulsive neurosis, anxiety, seizure, Alzheimer's disease, Parkinson's disease, Huntington's chorea, psychosis, schizophrenia, suicidal tendency, sleep disorder, appetite disorder and migraine.
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