Invention Application
- Patent Title: Indanone Potentiators of Metabotropic Glutamate Receptors
- Patent Title (中): 代谢型谷氨酸受体的茚酮电位器
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Application No.: US11658490Application Date: 2005-07-26
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Publication No.: US20080312286A1Publication Date: 2008-12-18
- Inventor: Anthony B. Pinkerton , Jean-Michel Vernier , Rowena Cube , John Hutchinson , Celine Bonnefous , Theodore Kamenecka
- Applicant: Anthony B. Pinkerton , Jean-Michel Vernier , Rowena Cube , John Hutchinson , Celine Bonnefous , Theodore Kamenecka
- International Application: PCT/US05/26867 WO 20050726
- Main IPC: C07D257/04
- IPC: C07D257/04 ; A61K31/41 ; C07C307/02 ; A61K31/18 ; C07C233/02 ; A61K31/454 ; C07D401/02 ; A61K31/192 ; C07C65/00 ; C07D213/80 ; A61K31/44 ; A61K31/343 ; C07D307/78 ; A61P25/00 ; A61P25/18 ; A61P25/24 ; A61P25/08
Abstract:
The present invention is directed to compounds which are potentiators of metabotropic glutamate receptors, including the mGluR2 receptor, and which are useful in the treatment or prevention of neurological and psychiatric disorders associated with glutamate dysfunction and diseases in which metabotropic glutamate receptors are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which metabotropic glutamate receptors are involved.
Information query
