Disclosed is a three-layer protective enclosure that provides resistance to water, dust, dirt, and bump protection for sensitive electronic devices. In one embodiment, an inner membrane layer is provided, which is a thin, flexible layer that protects portions of the electronic device and allows the user to interact with keyboards, push buttons and other interactive features of the electronic device. A protective hard shell fits tightly over the membrane and provides additional sealing and rigidity to the protective enclosure. A stretchable cushion layer is placed over the hard shell which conforms to the hard shell and seals moisture, dust and dirt from entering the hard shell. The stretchable cushion layer provides cushioning and also allows access to certain controls on the electronic device. In another embodiment, a touch screen cover may be used with, or without, a membrane over other portions of the electronic device.