发明申请
US20080319057A1 2-Phenylethylamino Derivatives as Calcium and/or Sodium Channel Modulators
有权
2-苯基乙基氨基衍生物作为钙和/或钠通道调节剂
- 专利标题: 2-Phenylethylamino Derivatives as Calcium and/or Sodium Channel Modulators
- 专利标题(中): 2-苯基乙基氨基衍生物作为钙和/或钠通道调节剂
-
申请号: US12158491申请日: 2006-11-29
-
公开(公告)号: US20080319057A1公开(公告)日: 2008-12-25
- 发明人: Florian Thaler , Mauro Napoletano , Cibele Sabido-David , Ermanno Moriggi , Carla Caccia , Laura Faravelli , Alessandra Restivo , Patricia Salvati
- 申请人: Florian Thaler , Mauro Napoletano , Cibele Sabido-David , Ermanno Moriggi , Carla Caccia , Laura Faravelli , Alessandra Restivo , Patricia Salvati
- 专利权人: NEWRON PHARMACEUTICALS S.p.A.
- 当前专利权人: NEWRON PHARMACEUTICALS S.p.A.
- 优先权: EP05028147.6 20051222
- 国际申请: PCT/EP2006/011443 WO 20061129
- 主分类号: A61K31/341
- IPC分类号: A61K31/341 ; C07C237/20 ; A61K31/165 ; C07D307/54
摘要:
2-Phenylethylamino substituted carboxamide derivatives of formula (I); wherein J, W, R0, R1, R2, R3, and R4 have the meanings as defined in the specification and pharmaceutically acceptable salts thereof, pharmaceutical compositions containing them as active ingredient and their use as sodium and/or calcium channel modulators useful in preventing alleviating and curing a wide range of pathologies, including neurological, psychiatric, cardiovascular, inflammatory, ophthalmic, urology, and gastrointestinal diseases where the above mechanisms have been described as playing a pathological role, are described.
公开/授权文献
信息查询