发明申请
- 专利标题： RANK LIGAND-BINDING POLYPEPTIDES
- 专利标题（中）： RANK配体结合多肽
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申请号： US11942684申请日： 2007-11-19
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公开(公告)号： US20090017499A1公开(公告)日： 2009-01-15
- 发明人: Jesper Mortensen Haaning , Torben Halkier
- 申请人： Jesper Mortensen Haaning , Torben Halkier
- 专利权人： Maxygen Holdings Ltd.
- 当前专利权人： Maxygen Holdings Ltd.
- 优先权： DKPA200100214 20010209; DKPA200100498 20010323
- 主分类号： C12P21/02
- IPC分类号： C12P21/02 ; C07K14/47 ; C12N15/62
摘要：
The present invention relates to a polypeptide having an amino acid sequence that differs from and is at least 70% identical to the amino acid sequence of hRANK, and which has a binding affinity to RANKL that is at least as high as the binding affinity of hRANK to RANKL, as determined by the functional competition assay described herein.
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