发明申请
US20090022727A1 INJECTABLE, NONAQUEOUS SUSPENSION WITH HIGH CONCENTRATION OF THERAPEUTIC AGENT
审中-公开
注意事项,治疗药物浓度高的非标准悬浮液
- 专利标题: INJECTABLE, NONAQUEOUS SUSPENSION WITH HIGH CONCENTRATION OF THERAPEUTIC AGENT
- 专利标题(中): 注意事项,治疗药物浓度高的非标准悬浮液
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申请号: US12020372申请日: 2008-01-25
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公开(公告)号: US20090022727A1公开(公告)日: 2009-01-22
- 发明人: Paul R. Houston , Guohua Chen , Andrew Sheung-King Luk
- 申请人: Paul R. Houston , Guohua Chen , Andrew Sheung-King Luk
- 专利权人: Alza Corp.
- 当前专利权人: Alza Corp.
- 主分类号: A61K39/395
- IPC分类号: A61K39/395 ; A61P35/00
摘要:
An injectable, nonaqueous suspension including at least one therapeutic agent suspended in a single component vehicle. The single component vehicle is a single amphiphilic material, such as a polyethoxylated castor oil or derivative thereof, a polyoxyethylene alkyl ether, a polyoxyethylene sorbitan fatty acid ester, a polyoxyethylene stearate, a block copolymer of polyethylene oxide-polypropylene oxide-polyethylene oxide, a block copolymer of polypropylene oxide-polyethylene oxide-polypropylene oxide, a tetra-functional block copolymer of polyethylene oxide-polypropylene oxide, or a tetra-functional block copolymer of polypropylene oxide-polyethylene oxide. A dosage kit that includes the injectable, nonaqueous suspension and a method of administering the injectable, nonaqueous suspension are also disclosed.
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