发明申请
- 专利标题: ALUMINUM-STORAGE DISEASE IMPROVING AGENT
- 专利标题(中): 铝储存疾病改善剂
-
申请号: US12178090申请日: 2008-07-23
-
公开(公告)号: US20090023806A1公开(公告)日: 2009-01-22
- 发明人: Tomonori Koizumi , Mitsuyoshi Isaka , Yoshiaki Shirai , Ryuuichi Mihara , Kazuyuki Ubukata , Akira Nakayama
- 申请人: Tomonori Koizumi , Mitsuyoshi Isaka , Yoshiaki Shirai , Ryuuichi Mihara , Kazuyuki Ubukata , Akira Nakayama
- 申请人地址: JP Tokyo
- 专利权人: AJINOMOTO CO. INC
- 当前专利权人: AJINOMOTO CO. INC
- 当前专利权人地址: JP Tokyo
- 优先权: JP2006-014904 20060124
- 主分类号: A61K31/225
- IPC分类号: A61K31/225 ; A61K31/194 ; A61P13/12
摘要:
A safe and easy-handling method to eliminate aluminum, which can easily accumulate in a dialysis patient body, in the course of a dialysis treatment and a dialysate used in the above method to eliminate aluminum ions from blood and tissues in the body are provided. A method to eliminate aluminum from a dialysis patient body characterized in that a dialysate mixed with aluminum complexing agents allows formation of complexes with aluminum to excrete aluminum in the form of aluminum complexes into the dialysis drain fluid is also provided. More specifically, the above-mentioned method to eliminate aluminum from the body employs preferably citric acid as an aluminum complexing agent, and the dialysate comprises general dialysate components and 1.7-2.4 mEq/L of citric acid as an aluminum complexing agent.
信息查询