A database management system in which a plurality of nodes form a database instance, each node including a communication manager for dynamically configuring inter-nodal communication resources. The communication manager receives communication resource allocation requests from clients or a self-tuning algorithm. A resource self-tuning mechanism allocates or de-allocates memory blocks used for communication resource elements dynamically in real time without cycling the instance. Memory blocks are de-allocated asynchronously by placing associated communication resource elements in quarantine until all communication resource elements associated with the memory block are quarantined.