发明申请
- 专利标题： Methods for detecting parenchymal plaques in vivo
- 专利标题（中）： 检测体内实质斑块的方法
-
申请号： US12009431申请日： 2008-01-18
-
公开(公告)号： US20090028789A1公开(公告)日： 2009-01-29
- 发明人: Joseph F. Poduslo , Geoffry L. Curran , Thomas M. Wengenack
- 申请人： Joseph F. Poduslo , Geoffry L. Curran , Thomas M. Wengenack
- 主分类号： A61K51/00
- IPC分类号： A61K51/00 ; A61K49/00 ; C07K16/18
摘要：
Methods for detecting parenchymal plaque deposits in the brain of a living mammal are described that include administering a polyamine modified, labeled polypeptide having specific binding affinity for the extracellular deposit, to the living mammal. Isolated β-amyloid peptides that are polyamine modified and labeled with a radioisotope or contrast agent also are described.
信息查询
