发明申请
- 专利标题: Novel carbapenem compound
- 专利标题(中): 新型碳青霉烯类化合物
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申请号: US11886949申请日: 2006-03-23
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公开(公告)号: US20090029964A1公开(公告)日: 2009-01-29
- 发明人: Makoto Sunagawa , Akira Sasaki , Takashi Tsukimura
- 申请人: Makoto Sunagawa , Akira Sasaki , Takashi Tsukimura
- 优先权: JP2005-088672 20050325
- 国际申请: PCT/JP2006/305777 WO 20060323
- 主分类号: A61K31/407
- IPC分类号: A61K31/407 ; C07D477/00 ; A61P31/04
摘要:
An orally administrable antibacterial agent which contains as an active ingredient a carbapenem compound represented by the formula [1] below, wherein R0 represents hydrogen atom or the like; R1 represents C1-C3 alkyl substituted by hydroxyl group or the like; R represents hydrogen atom or a group which regenerates a carboxyl group by hydrolysis in a living body; L represents a single bond, methylene, —OCH2(CO)— or the like; and Het represents a group represented by the following formula [2], wherein m and n independently represent 0 or 1; A and B independently represent methylene, carbonyl or the like; Y represents methylene, ethylene, oxygen atom, —OCH2—, —NRaCH2— (wherein Ra represents hydrogen atom, optionally substituted C1-C4 alkyl group or the like) or the like.
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