发明申请
- 专利标题: Amylases for Pharmaceutical Use
- 专利标题(中): 药用淀粉酶
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申请号: US11917551申请日: 2006-06-16
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公开(公告)号: US20090035293A1公开(公告)日: 2009-02-05
- 发明人: Allan Svendsen , Peter Collin Gregory
- 申请人: Allan Svendsen , Peter Collin Gregory
- 申请人地址: DK Bagsvaerd DE Hannover
- 专利权人: Novozymes A/S,Solvay Pharmaceuticals
- 当前专利权人: Novozymes A/S,Solvay Pharmaceuticals
- 当前专利权人地址: DK Bagsvaerd DE Hannover
- 优先权: DKPA200500931 20050624
- 国际申请: PCT/DK2006/000354 WO 20060616
- 主分类号: A61K38/43
- IPC分类号: A61K38/43 ; C12N9/26 ; A61P1/00
摘要:
The pharmaceutical use of amylases related to Bacillus alpha-amylases of SEQ ID NOs: 1-3, optionally in combination with a lipase and/or a protease. Examples of medical indications are: Treatment of digestive disorders, pancreatic exocrine insufficiency (PEI), pancreatitis, cystic fibrosis, diabetes type I, and/or diabetes type II. The amylases of SEQ ID NOs: 1-3 are variants of amylases from Bacillus stearothermophilus, Bacillus licheniformis and Bacillus sp. The amylases of the invention have an improved efficacy in vivo, an improved pH-profile, a high specific activity, and/or an improved starch degradation profile.
公开/授权文献
- US08017351B2 Amylases for pharmaceutical use 公开/授权日:2011-09-13
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