发明申请
- 专利标题： GIP ANALOG AND HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES
- 专利标题（中）： 具有可选性能的GIP模拟和混合多糖
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申请号： US11816095申请日： 2006-02-10
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公开(公告)号： US20090036364A1公开(公告)日： 2009-02-05
- 发明人: Odile Esther Levy , Alain D. Baron , Lawrence J D'Souza , Mary Erickson , Soumitra S. Ghosh , Michael R. Hanley , Samuel Janssen , Carolyn M. Jodka , Diana Y. Lewis , Christine M. Mack , David G. Parkes , Richard A. Pittner , Christopher J. Soares , Ved Srivastava , Andrew A. Young
- 申请人： Odile Esther Levy , Alain D. Baron , Lawrence J D'Souza , Mary Erickson , Soumitra S. Ghosh , Michael R. Hanley , Samuel Janssen , Carolyn M. Jodka , Diana Y. Lewis , Christine M. Mack , David G. Parkes , Richard A. Pittner , Christopher J. Soares , Ved Srivastava , Andrew A. Young
- 申请人地址： US CA San Diego
- 专利权人： Amylin Pharmaceuticals, Inc.
- 当前专利权人： Amylin Pharmaceuticals, Inc.
- 当前专利权人地址： US CA San Diego
- 国际申请： PCT/US2006/005020 WO 20060210
- 主分类号： A61K38/22
- IPC分类号： A61K38/22 ; C07K14/47 ; A61P3/10
摘要：
The present invention relates generally to novel GIP analogs and GIP hybrid polypeptides with selectable properties, useful as agents for the treatment and prevention of metabolic diseases and disorders, for example those which can be alleviated by control plasma glucose levels, insulin levels, and/or insulin secretion, positive inotropic effects, reduction of catabolic effects, slowing of gastric emptying. Such conditions and disorders include, but are not limited to, hypertension, dyslipidemia, cardiovascular disease, eating disorders, critical care, insulin-resistance, obesity, and diabetes mellitus of any kind, including type 1, type 2, and gestational diabetes.
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