发明申请
- 专利标题: Novel CXCR4 Antagonist and Use Thereof
- 专利标题(中): 新型CXCR4拮抗剂及其用途
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申请号: US12087160申请日: 2006-12-27
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公开(公告)号: US20090036416A1公开(公告)日: 2009-02-05
- 发明人: Nobutaka Fujii , Itaru Hamachi , Akio Ojida , Hirokazu Tamamura , Hideki Nakashima
- 申请人: Nobutaka Fujii , Itaru Hamachi , Akio Ojida , Hirokazu Tamamura , Hideki Nakashima
- 申请人地址: JP Kyoto
- 专利权人: Kyoto University
- 当前专利权人: Kyoto University
- 当前专利权人地址: JP Kyoto
- 优先权: JP2005-379167 20051228
- 国际申请: PCT/JP2006/326069 WO 20061227
- 主分类号: A61K31/555
- IPC分类号: A61K31/555
摘要:
A novel non-peptide CXCR4 antagonist has a low molecular-weight and uses various aromatic compounds, each containing a dipicolylamine-zinc complex. This CXCR4 antagonist finds use, e.g., as an anti-HIV agent, a metastasis inhibitor for a malignant tumor, and a chronic rheumatoid arthritis treatment and/or prevention agent.
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