发明申请
US20090042908A1 AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR BETA-SECRETASE MODULATION
审中-公开
AMINO-5-（6-MEMBERED）异环糊精化合物及其用于BETA-分泌酶调节的用途
- 专利标题： AMINO-5-(6-MEMBERED)HETEROARYLIMIDAZOLONE COMPOUNDS AND THE USE THEREOF FOR BETA-SECRETASE MODULATION
- 专利标题（中）： AMINO-5-（6-MEMBERED）异环糊精化合物及其用于BETA-分泌酶调节的用途
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申请号： US12248996申请日： 2008-10-10
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公开(公告)号： US20090042908A1公开(公告)日： 2009-02-12
- 发明人: Ping Zhou , Michael Sotirios Malamas , Yanfang Li , Albert Jean Robichaud , Dominick Anthony Quagliato
- 申请人： Ping Zhou , Michael Sotirios Malamas , Yanfang Li , Albert Jean Robichaud , Dominick Anthony Quagliato
- 申请人地址： US NJ Madison
- 专利权人： Wyeth
- 当前专利权人： Wyeth
- 当前专利权人地址： US NJ Madison
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; A61K31/4439 ; A61K31/444 ; A61P25/28 ; A61P25/00 ; A61K31/506
摘要：
The present invention provides a 2-amino-5-heteroaryl-5-phenylimidazolone compound of formula I The present invention also provides methods for the use thereof to inhibit β-secretase (BACE) and treat β-amyloid deposits and neurofibrillary tangles