Targeted advertising is one of the major attractions of wireless handheld devices since it lends itself to focused delivery of advertisements to target groups selected based on multiple criteria. To do this it is necessary to identify the target groups from the large number of personal profile criteria that includes user profiles, demographics, response preferences, as well as the history of responses, and generating advertisements for each such group. The advertisements have to take into account the preferences of the group and the objective of the advertisement campaign. In one embodiment of the invention, target groups are identified based on preferences to define and organize advertising campaigns, resulting in personalized advertisements.